Imagine a world where tooth loss is no longer a permanent thing. Thanks to a young drug, that future may be closer than we think.
Japanese researchers are on the verge of a dental revolution. After years of promising results in animal studies with mice and ferrets, they are finally ready to test a basic drug that could potentially regenerate. adult teeth.
Dentist Dr. Niyati Arora explained that all the research revolves around one gene: USAG -1 (gene related to uterine sensitivity). “USAG-1 controls the number of teeth that must form in a person by preventing the growth of potential bacteria. Therefore, using something that blocks this genetic activity, such as an anti-USAG 1 antibody, would be a wonderful step forward in tooth regeneration,” explains Dr Arora.
By eliminating this protein, researchers believe they can stimulate the development of new teeth, providing a potential cure for the millions of people suffering from tooth loss.
The invention also offers hope to people who have lost one or more teeth as it can offer a non-invasive procedure option. (Source: Freepik)
The first phase of human trials will take place at Kyoto University and Kitano Hospital in Japan. 30 elderly men between the ages of 30 and 64, each missing at least one molar, will participate. The trial will last 11 months, and the researchers intend to expand it to include children born with dental problems and older adults in later stages.
Dr. Arora said that if these tests are successful, they will solve the biggest challenge of children suffering from anodontia, which is a condition where some or all of the teeth are missing since birth. Currently, the only solution for this condition is dentures or implants.
The establishment also gives hope to the people who have it they lost one or more of their teeth as it will offer a non-invasive procedure option. “It will improve the quality of life of many people. It can reduce long-term costs added to dental treatment,” said Dr Arora in an interview.
Not only this, it can lead to potential breakthroughs in the field of research and innovation and help in the development of regenerative medicine and stem cell research.
Although the drug holds great promise and has been in development since 2005, it may be several years before it is available for general use. However, if all goes according to plan, it could revolutionize dental care as soon as 2023 and provide a long-awaited option for people with tooth loss.
CITY DISCLAIMER: This article is based on information from the public domain and/or experts we spoke to. Always consult your doctor before starting any procedure.
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